MOMbrane

Application: International PhD Program in Molecular Cell Biology

Important Dates:

Application deadline: 15.03.2021

Invitation of candidates for an interview: until 31.03.2021

Assessment of selected candidates (in Tübingen or online): 12.-16.04.2021

Final notification of candidates: until 30.04.2021

Start of the PhD projects in Tübingen: June – Sept. 2021

Further information:

Applicants will be evaluated based on academic records and prior research experience. Appropriate applicants will be invited for personal interview (online or in Tübingen).

The recruitment process will be managed by a Selection Committee.

Doctoral fellows will be appointed upon a match between their preferences and the availability of the projects.

The potential list of available project leaders (see Application form) includes a new project by Junior Prof. Jennifer Ewald, which is not included yet in this web site.
Here is a link to the web site of the Ewald group.

To apply for a PhD position in this program, please download the documents below and carefully read the Application Guide.

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Application Guide

Application Form

Reference Form

The multifaceted functions and dynamics of the mitochondrial outer membrane (MOM)

Importance of the mitochondrial outer membrane (MOM)

The mitochondrial outer membrane (MOM) mediates numerous interactions between mitochondria and the rest of the cell. It plays a central role in: mitophagy, apoptosis, motility and morphology of the organelle, transfer of proteins and lipids to and from other compartments, immune response, and exchange of metabolites with the cytosol. Despite its obvious importance, the MOM is currently understudied, making our initiative highly relevant and unique. All the included projects are tightly interconnected and deal with various aspects of the same biological question: How are mitochondrial diversity, dynamics and functions coordinated and regulated at the level of the MOM?

Our goal

We intend to achieve comprehensive understanding of the structure, function, regulation, and biogenesis of the MOM.

Interdisciplinary approach

On the one end of the spectrum, we will use yeast cells to study basic mitochondrial mechanisms, and on the other, we will utilize induced pluripotent stem cells and mouse models to investigate MOM-related pathomechanisms of human diseases. Our RTG will bring together different disciplines such as protein analytics, structural biology, biophysics, cell biology, and modern imaging.

Training concept

All fellows participating in this RTG will benefit from an intense program of training measures. Our aim is to provide a cohort of young researchers the appropriate multidisciplinary background and knowhow in mitochondrial biology and to train them in techniques needed to study it. In addition, we will include in our RTG a wide spectrum of career promoting, non-scientific activities.