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- Projects
- P1 (Kahle) - VDAC as an intersection of the mitophagy pathway
- P2 (Macek) -Dynamics of the mitochondrial outer membrane proteome in mitophagy and apoptosis
- P3 (Garcia Saez) - Interplay between the Bcl-2 proteins and Drp1: a biophysical characterization
- P4 (Jansen) - Localized translation of proteins at the mitochondrial outer membrane
- P5 (Rapaport) - Association of PINK1 with the mitochondrial outer membrane
- P6 (Dimmer) - Identification of the mammalian homolog of fungal ERMES complex
- P7 (Fitzgerald) - Miro function and relevance to Parkinson’s disease
- P8 (Rothbauer) - Nano- and Chromobodies for structural and functional analysis of the MOM associated components Miro1, Milton/TRAK and Drp1
- P9 (Schäffer) - The mechanics of MOM-associated molecular machines
- P10 (Stehle) - Structure-function analysis of the human mitochondrial GTPase Miro
- P11 (Proikas-Cezanne) - Mitochondrial outer membrane as signaling hub in the control of autophagy
- P12 (Ewald) - Remodeling of the mitochondrial outer membrane during the cell division cycle
- Publications
- Characterization of the targeting signal in mitochondrial β-barrel proteins
- The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy.
- Quantitative phosphoproteome analysis of Bacillus subtilis reveals novel substrates of the kinase PrkC and phosphatase PrpC.
- Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane division.
- Here, there, everywhere. mRNA localization in budding yeast.
- The role of Djp1 in import of the mitochondrial protein Mim1 demonstrates specificity between a cochaperone and its substrate protein.
- Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis.
- Monoamine oxidase-A knockdown in human neuroblastoma cells reveals protection against mitochondrial toxins.
- A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells.
- Kinesin rotates unidirectionally and generates torque while walking on microtubules.
- Structural basis of head to head polyketide fusion by CorB.
- Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease
- The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism
- Drp1 modulates mitochondrial stress responses to mitotic arrest
- A novel epitope tagging system to visualize and monitor antigens in live cells with chromobodies
- Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors.
- Generation of R272Q, S156A and K572R RHOT1/Miro1 Point Mutations in iPSCs from a Healthy Individual using FACS-assisted CRISPR/Cas9 Genome Editing
- Regulation of mitochondrial cargo-selective autophagy by post-translational modifications
- Temporal Analysis of Protein Ubiquitylation and Phosphorylation During Parkin-dependent Mitophagy
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